Main Article Content
Abstract
Prematuritas merupakan salah satu masalah yang sering terjadi pada bayi baru lahir yang dapat disebabkan oleh berbagai faktor. Salah satu permasalahan fatal yang umum terjadi pada bayi prematur adalah masalah pernapasan yang membutuhkan intervensi tepat. Terapi oksigen untuk bayi prematur dengan insufisiensi pernapasan bertujuan untuk mencegah atau memoderasi efek hipoksemia pada sistem saraf pusat, paru-paru dan organ lainnya. Penelitian ini bertujuan untuk mengidentifikasi terapi oksigen yang digunakan untuk pencegahan hipoksia pada bayi prematur di Neonatal Intensive Care Unit (NICU). Metode penelitian ini menggunakan narrative review. Artikel dikumpulkan dari Pubmed, ScienceDirect, EBSCOhost, SAGE Journals, Google Scholar, dan Taylor & Francis. Kata kunci yang digunakan yaitu premature infants, preterm infants, oxygenation management, hypoxia, hypoxic, hypoxemic, hypoxemia, prevention, intervention, treatment dengan boolean “OR” dan “AND”. Kriteria inklusi yaitu artikel dalam Bahasa Inggris, free full-text, dan dipublikasikan dari tahun 2017 hingga 2022. Hasil pencarian mendapatkan artikel sebanyak 2.351 dan hanya enam artikel yang memenuhi kriteria dan kemudian dilakukan analisis. Terapi oksigen pada bayi prematur untuk mencegah hipoksia dapat meliputi pemberian oksigen menggunakan nasal kanul, humidified high flow nasal cannula, nasal continuous positive airway pressure, ventilator dan automated oxygen control; pemantauan saturasi oksigen; dan positioning. Kesimpulan yang didapatkan yaitu intervensi terapi oksigen yang digunakan tergantung pada kondisi dan kebutuhan setiap bayi prematur. Terapi oksigen pada bayi prematur berguna menyediakan oksigen yang cukup ke jaringan untuk menghindari metabolisme dan mempertahankan pertumbuhan otak yang optimal. Perawat berperan dalam memantau dan menyesuaikan perawatan untuk memastikan bayi mendapatkan dukungan yang optimal
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References
- Ali, S. K. M., Mohammed, N., Qureshi, N., & Gupta, S. (2021). Oxygen therapy in preterm infants: recommendations for practice. Paediatrics and Child Health (United Kingdom), 31(1), 1–6. https://doi.org/10.1016/j.paed.2020.10.001
- Artal, R., & Rubenfeld, S. (2017). Ethical issues in research. Best Practice and Research: Clinical Obstetrics and Gynaecology, 43, 107–114. https://doi.org/10.1016/j.bpobgyn.2016.12.006
- Askie, L. M., Darlow, B. A., & Finer, N. (2018). Association Between Oxygen Saturation Targeting and Death or Disability in Extremely Preterm Infants in the Neonatal Oxygenation Prospective Meta-analysis Collaboration. JAMA, 319(21), 2190–2201. https://doi.org/doi:10.1001/jama.2018.5725
- Caswini, N., Rustina, Y., & Efendi, D. (2021). Perawatan Metode Kanguru (PMK) dapat mempercepat proses penyapihan penggunaan High Flow Nasal (HFN) pada bayi prematur. NURSCOPE: Jurnal Penelitian Dan Pemikiran Ilmiah Keperawatan, 7(1), 1. https://doi.org/10.30659/nurscope.7.1.1-5
- Claure, N., & Bancalari, E. (2019). Targeting arterial oxygen saturation by closed-loop control of inspired oxygen in preterm infants. Clinics in Perinatology, 46(3), 567–577. https://doi.org/https://doi.org/10.1016/j.clp.2019.05.007
- Fathabadi, O. S., Gale, T. J., Olivier, J. C., & Dargaville, P. A. (2016). Automated control of inspired oxygen for preterm infants: What we have and what we need. Biomedical Signal Processing and Control, 28, 9–18. https://doi.org/https://doi.org/10.1016/j.bspc.2016.03.002
- Ferrari, R. (2015). Writing narrative style literature reviews. Medical Writing, 24(4), 230–235. https://doi.org/10.1179/2047480615z.000000000329
- Heuvel, M. E. N. van den, Zanten, H. A. van, Bachman, T. E., Pas, A. B. Te, Kaam, A. H. van, & Onland, W. (2018). Optimal target range of closed-loop inspired oxygen support in preterm infants: a randomized cross-over study. The Journal of Pediatrics, 97, 36–41.
- Hong, H., Li, X. xia, Li, J., & Zhang, Z. qun. (2021). High-flow nasal cannula versus nasal continuous positive airway pressure for respiratory support in preterm infants: a meta-analysis of randomized controlled trials. Journal of Maternal-Fetal and Neonatal Medicine, 34(2), 259–266. https://doi.org/10.1080/14767058.2019.1606193
- Huang, J., Qian, Y., Gao, M., Ding, H., Zhang, L., & Jia, R. (2020). Analysis of factors related to preterm birth: A retrospective study at Nanjing Maternity and Child Health Care Hospital in China. Medicine (United States), 99(28), E21172. https://doi.org/10.1097/MD.0000000000021172
- Kaam, A. H. van, Hummler, H. D., Wilinska, M., Swietlinski, J., Lal, M. ., Pas, A. B. te, & Bachman, T. E. (2015). Automated versus manual oxygen control with different saturation targets and modes of respiratory support in preterm infants. The Journal of Pediatrics, 167(3), 45–550.
- Kenner, C., & Boykova, M. V. (2021). Neonatal nursing care handbook: an evidence-based approach to conditions and procedures. Springer Publishing Company.
- Lin, X., & Yang, C. (2022). A comparison of the effect of bi-level positive airway pressure and synchronized intermittent mandatory ventilation in preterm infants with respiratory distress syndrome. Journal of Maternal-Fetal and Neonatal Medicine, 35(25), 5393–5399. https://doi.org/10.1080/14767058.2021.1881059
- Martin, R. J., Fanaroff, A. A., & Walsh, M. C. (2020). Fanaroff and Martin’s Neonatal-Perinatal Medicine: Diseases of the Fetus and Infant (11th ed.). Elsevier.
- Rohsiswatmo, R., & Amandito, R. (2019). Optimalisasi Pertumbuhan Bayi Prematur dan Pasca Prematur di Indonesia; Mengacu pada Pedoman Nutrisi Bayi Prematur di Rumah Sakit Cipto Mangunkusumo. Sari Pediatri, 21(4), 262–270. https://doi.org/10.14238/sp21.4.2019.262-71
- Salverda, H. H., Cramer, S. J. E., Witlox, R. S. G. M., Gale, T. J., Dargaville, P. A., Pauws, S. C., & Te Pas, A. B. (2022). Comparison of two devices for automated oxygen control in preterm infants: A randomised crossover trial. Archives of Disease in Childhood: Fetal and Neonatal Edition, 107(1), F20–F25. https://doi.org/10.1136/archdischild-2020-321387
- Salverda, H. H., Oldenburger, N. J., Rijken, M., Pauws, S. C., Dargaville, P. A., & te Pas, A. B. (2021). The effect of automated oxygen control on clinical outcomes in preterm infants: a pre- and post-implementation cohort study. European Journal of Pediatrics, 180(7), 2107–2113. https://doi.org/10.1007/s00431-021-03982-8
- Saugstad, O. D., Kapadia, V., & Oei, J. L. (2021). Oxygen in the First Minutes of Life in Very Preterm Infants. Neonatology, 118(2), 218–224. https://doi.org/10.1159/000516261
- Shin, J., Park, K., Lee, E. H., & Choi, B. M. (2017). Humidified high flow nasal cannula versus nasal continuous positive airway pressure as an initial respiratory support in preterm infants with respiratory distress: A randomized, controlled non-inferiority trial. Journal of Korean Medical Science, 32(4), 650–655. https://doi.org/10.3346/jkms.2017.32.4.650
- Travers, C. P., Carlo, W. A., Nakhmani, A., Bhatia, S., Gentle, S. J., Amperayani, V. N. S. A., … Ambalavanan, N. (2018). Environmental or Nasal Cannula Supplemental Oxygen for Preterm Infants: A Randomized Cross-Over Trial. Journal of Pediatrics, 200, 98–103. https://doi.org/10.1016/j.jpeds.2018.03.010
- Vali, P., Underwood, M., & Lakshminrusimha, S. (2019). Hemoglobin oxygen saturation targets in the neonatal intensive care unit: Is there a light at the end of the tunnel?1. Canadian Journal of Physiology and Pharmacology, 97(3), 174–182. https://doi.org/10.1139/cjpp-2018-0376
- van Zanten, H. A., Tan, R. N. G. B., van den Hoogen, A., Lopriore, E., & te Pas, A. B. (2015). Compliance in oxygen saturation targeting in preterm infants: a systematic review. European Journal of Pediatrics, 174(12), 1561–1572. https://doi.org/10.1007/s00431-015-2643-0
- Warakomska, M., Bachman, T. E., & Wilinska, M. (2019). Evaluation of two SpO2 alarm strategies during automated FiO2 control in the NICU: A randomized crossover study. BMC Pediatrics, 19(1), 5–12. https://doi.org/10.1186/s12887-019-1496-5
- Wilinska, M., Bachman, T., Swietlinski, J., & Jakiel, G. (2015). Quicker response results in better SpO2 control - A comparison of 3 FiO2-titration strategies in ventilated preterm infants. Annals of Agricultural and Environmental Medicine, 22(4), 708–712. https://doi.org/10.5604/12321966.1185781
- Zeitlin, J., Manktelow, B. N., Piedvache, A., Cuttini, M., Boyle, E., Van Heijst, A., … Maier, R. F. (2016). Use of evidence based practices to improve survival without severe morbidity for very preterm infants: Results from the EPICE population based cohort. BMJ (Online), 354, 1–10. https://doi.org/10.1136/bmj.i2976
References
Ali, S. K. M., Mohammed, N., Qureshi, N., & Gupta, S. (2021). Oxygen therapy in preterm infants: recommendations for practice. Paediatrics and Child Health (United Kingdom), 31(1), 1–6. https://doi.org/10.1016/j.paed.2020.10.001
Artal, R., & Rubenfeld, S. (2017). Ethical issues in research. Best Practice and Research: Clinical Obstetrics and Gynaecology, 43, 107–114. https://doi.org/10.1016/j.bpobgyn.2016.12.006
Askie, L. M., Darlow, B. A., & Finer, N. (2018). Association Between Oxygen Saturation Targeting and Death or Disability in Extremely Preterm Infants in the Neonatal Oxygenation Prospective Meta-analysis Collaboration. JAMA, 319(21), 2190–2201. https://doi.org/doi:10.1001/jama.2018.5725
Caswini, N., Rustina, Y., & Efendi, D. (2021). Perawatan Metode Kanguru (PMK) dapat mempercepat proses penyapihan penggunaan High Flow Nasal (HFN) pada bayi prematur. NURSCOPE: Jurnal Penelitian Dan Pemikiran Ilmiah Keperawatan, 7(1), 1. https://doi.org/10.30659/nurscope.7.1.1-5
Claure, N., & Bancalari, E. (2019). Targeting arterial oxygen saturation by closed-loop control of inspired oxygen in preterm infants. Clinics in Perinatology, 46(3), 567–577. https://doi.org/https://doi.org/10.1016/j.clp.2019.05.007
Fathabadi, O. S., Gale, T. J., Olivier, J. C., & Dargaville, P. A. (2016). Automated control of inspired oxygen for preterm infants: What we have and what we need. Biomedical Signal Processing and Control, 28, 9–18. https://doi.org/https://doi.org/10.1016/j.bspc.2016.03.002
Ferrari, R. (2015). Writing narrative style literature reviews. Medical Writing, 24(4), 230–235. https://doi.org/10.1179/2047480615z.000000000329
Heuvel, M. E. N. van den, Zanten, H. A. van, Bachman, T. E., Pas, A. B. Te, Kaam, A. H. van, & Onland, W. (2018). Optimal target range of closed-loop inspired oxygen support in preterm infants: a randomized cross-over study. The Journal of Pediatrics, 97, 36–41.
Hong, H., Li, X. xia, Li, J., & Zhang, Z. qun. (2021). High-flow nasal cannula versus nasal continuous positive airway pressure for respiratory support in preterm infants: a meta-analysis of randomized controlled trials. Journal of Maternal-Fetal and Neonatal Medicine, 34(2), 259–266. https://doi.org/10.1080/14767058.2019.1606193
Huang, J., Qian, Y., Gao, M., Ding, H., Zhang, L., & Jia, R. (2020). Analysis of factors related to preterm birth: A retrospective study at Nanjing Maternity and Child Health Care Hospital in China. Medicine (United States), 99(28), E21172. https://doi.org/10.1097/MD.0000000000021172
Kaam, A. H. van, Hummler, H. D., Wilinska, M., Swietlinski, J., Lal, M. ., Pas, A. B. te, & Bachman, T. E. (2015). Automated versus manual oxygen control with different saturation targets and modes of respiratory support in preterm infants. The Journal of Pediatrics, 167(3), 45–550.
Kenner, C., & Boykova, M. V. (2021). Neonatal nursing care handbook: an evidence-based approach to conditions and procedures. Springer Publishing Company.
Lin, X., & Yang, C. (2022). A comparison of the effect of bi-level positive airway pressure and synchronized intermittent mandatory ventilation in preterm infants with respiratory distress syndrome. Journal of Maternal-Fetal and Neonatal Medicine, 35(25), 5393–5399. https://doi.org/10.1080/14767058.2021.1881059
Martin, R. J., Fanaroff, A. A., & Walsh, M. C. (2020). Fanaroff and Martin’s Neonatal-Perinatal Medicine: Diseases of the Fetus and Infant (11th ed.). Elsevier.
Rohsiswatmo, R., & Amandito, R. (2019). Optimalisasi Pertumbuhan Bayi Prematur dan Pasca Prematur di Indonesia; Mengacu pada Pedoman Nutrisi Bayi Prematur di Rumah Sakit Cipto Mangunkusumo. Sari Pediatri, 21(4), 262–270. https://doi.org/10.14238/sp21.4.2019.262-71
Salverda, H. H., Cramer, S. J. E., Witlox, R. S. G. M., Gale, T. J., Dargaville, P. A., Pauws, S. C., & Te Pas, A. B. (2022). Comparison of two devices for automated oxygen control in preterm infants: A randomised crossover trial. Archives of Disease in Childhood: Fetal and Neonatal Edition, 107(1), F20–F25. https://doi.org/10.1136/archdischild-2020-321387
Salverda, H. H., Oldenburger, N. J., Rijken, M., Pauws, S. C., Dargaville, P. A., & te Pas, A. B. (2021). The effect of automated oxygen control on clinical outcomes in preterm infants: a pre- and post-implementation cohort study. European Journal of Pediatrics, 180(7), 2107–2113. https://doi.org/10.1007/s00431-021-03982-8
Saugstad, O. D., Kapadia, V., & Oei, J. L. (2021). Oxygen in the First Minutes of Life in Very Preterm Infants. Neonatology, 118(2), 218–224. https://doi.org/10.1159/000516261
Shin, J., Park, K., Lee, E. H., & Choi, B. M. (2017). Humidified high flow nasal cannula versus nasal continuous positive airway pressure as an initial respiratory support in preterm infants with respiratory distress: A randomized, controlled non-inferiority trial. Journal of Korean Medical Science, 32(4), 650–655. https://doi.org/10.3346/jkms.2017.32.4.650
Travers, C. P., Carlo, W. A., Nakhmani, A., Bhatia, S., Gentle, S. J., Amperayani, V. N. S. A., … Ambalavanan, N. (2018). Environmental or Nasal Cannula Supplemental Oxygen for Preterm Infants: A Randomized Cross-Over Trial. Journal of Pediatrics, 200, 98–103. https://doi.org/10.1016/j.jpeds.2018.03.010
Vali, P., Underwood, M., & Lakshminrusimha, S. (2019). Hemoglobin oxygen saturation targets in the neonatal intensive care unit: Is there a light at the end of the tunnel?1. Canadian Journal of Physiology and Pharmacology, 97(3), 174–182. https://doi.org/10.1139/cjpp-2018-0376
van Zanten, H. A., Tan, R. N. G. B., van den Hoogen, A., Lopriore, E., & te Pas, A. B. (2015). Compliance in oxygen saturation targeting in preterm infants: a systematic review. European Journal of Pediatrics, 174(12), 1561–1572. https://doi.org/10.1007/s00431-015-2643-0
Warakomska, M., Bachman, T. E., & Wilinska, M. (2019). Evaluation of two SpO2 alarm strategies during automated FiO2 control in the NICU: A randomized crossover study. BMC Pediatrics, 19(1), 5–12. https://doi.org/10.1186/s12887-019-1496-5
Wilinska, M., Bachman, T., Swietlinski, J., & Jakiel, G. (2015). Quicker response results in better SpO2 control - A comparison of 3 FiO2-titration strategies in ventilated preterm infants. Annals of Agricultural and Environmental Medicine, 22(4), 708–712. https://doi.org/10.5604/12321966.1185781
Zeitlin, J., Manktelow, B. N., Piedvache, A., Cuttini, M., Boyle, E., Van Heijst, A., … Maier, R. F. (2016). Use of evidence based practices to improve survival without severe morbidity for very preterm infants: Results from the EPICE population based cohort. BMJ (Online), 354, 1–10. https://doi.org/10.1136/bmj.i2976